Detecting circulating tumor cells (CTCs) remains a significant analytical challenge due to their extreme rarity. Only about 1–10 CTCs are typically present per mL of whole blood, and current technologies often must identify a single CTC among nearly 10 million nucleated blood cells. This rarity drives the need for highly sensitive platforms capable of resolving these exceptionally scarce events.
The Axon Dx imaging systems were originally developed to address the technical challenges of circulating tumor cell (CTC) detection and have evolved into adaptable rare-cell research platforms.
Key capabilities include:
Multi-channel fluorescence imaging
Automated whole-slide scanning
High-resolution digital image capture
AI-assisted cellular identification
Structured data archiving
AXON Dx™ Products
Axon Dx’s nCyte™ technology
Axon Dx’s nCyte™ technology scans un-enriched blood samples in minutes, finds all classes of rare cells such as CTCs shed by solid tumors, and offers morphological and proteomic and genomic characterization of positive cells.
AXON Dx’s nCYTE™
Axon Dx technology supports research in:
Circulating tumor cell (CTC) studies
Rare cell analysis such as circulating stromal cells and circulating endothelial cells
Translational oncology research
Assay development and validation
Analytical Reagents Reduced 10-fold
Analytical Run Time— Less than 10 Minutes!
Analytical Detection Limit— 1 CTC Cell in 10 Million
AXON Dx™ Products
Collaboration
Axon Dx engages in research collaborations and strategic technology partnerships within the rare-cell detection ecosystem.